What are the other health consequences of drug addiction?

People with addiction often have one or more associated health issues, which could include lung or heart disease, stroke, cancer, or mental health conditions. Imaging scans, chest X-rays, and blood tests can show the damaging effects of long-term drug use throughout the body.

For example, it is now well-known that tobacco smoke can cause many cancers, methamphetamine can cause severe dental problems, known as meth mouth, and opioids can lead to overdose and death. In addition, some drugs, such as inhalants, may damage or destroy nerve cells, either in the brain or the peripheral nervous system (the nervous system outside the brain and spinal cord).

Drug use can also increase the risk of contracting infections. HIV and hepatitis C (a serious liver disease) can occur from sharing injection equipment or from unsafe practices such as condomless sex.40,41 Infection of the heart and its valves (endocarditis) and skin infection (cellulitis) can occur after exposure to bacteria by injection drug use.42

Does drug use cause other mental disorders or vice versa?

Drug use and other mental illness often co-exist. In some cases, mental disorders such as anxiety, depression, or schizophrenia may come before addiction. In other cases, drug use may trigger or worsen those mental health conditions, particularly in people with specific vulnerabilities.43,44

Some people with disorders like anxiety or depression may use drugs in an attempt to alleviate psychiatric symptoms. This may exacerbate their mental illness in the long run and increase the risk of developing an addiction.43,44 Treatment for all conditions should happen concurrently.

How can addiction harm other people?

The Impact of Addiction Can Be Far-Reaching

  • Cardiovascular disease
  • Stroke
  • Cancer
  • HIV/AIDS
  • Hepatitis B and C
  • Lung disease
  • Mental disorders

How can addiction harm other people?

Beyond the harmful consequences for the person with the addiction, drug use can cause serious health problems for others. Some of the more severe consequences of addiction are:

Negative effects of drug use while pregnant or breastfeeding: 

A mother’s substance or medication use during pregnancy can cause her baby to go into withdrawal after it’s born, which is called neonatal abstinence syndrome (NAS). Symptoms will differ depending on the substance used but may include tremors, problems with sleeping and feeding, and even seizures.45 Some drug-exposed children will have developmental problems with behavior, attention, and thinking. Ongoing research is exploring if these effects on the brain and behavior extend into the teen years, causing continued developmental problems. In addition, some substances can make their way into a mother’s breast milk. Scientists are still learning about the long-term effects on a child who is exposed to drugs through breastfeeding.

Increased risk of motor vehicle accidents: Use of illicit drugs or misuse of prescription drugs can make driving a car unsafe—just like driving after drinking alcohol. Drugged driving puts the driver, passengers, and others who share the road at risk. In 2016, almost 12 million people ages 16 or older reported driving under the influence of illicit drugs, including marijuana.50 After alcohol, marijuana is the drug most often linked to impaired driving. Research studies have shown the negative effects of marijuana on drivers, including an increase in lane weaving, poor reaction time, and altered attention to the road.


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